Laser light may stop chemo mouth sores in children

NCT ID NCT03983369

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether low-level laser therapy can prevent severe mouth sores (mucositis) caused by chemotherapy in children and young adults aged 4 to 25. The laser is a painless, non-heating light applied to the mouth before chemotherapy. The trial is double-blind and placebo-controlled, meaning some participants get a sham laser. If successful, it could offer a safe, drug-free way to reduce a common and painful side effect of cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Low-level laser therapy (LLLT) device

What this could lead to

If it works, this could give doctors a simple, non-drug way to prevent painful mouth sores in young cancer patients undergoing chemotherapy.

What could go wrong

This is a Phase 3 trial, but the effect may be modest or no better than placebo. The laser device requires cooperation from children, which may limit its use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

stomatitis chemotherapy-induced oral mucositis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Rennes

    RECRUITING

    Rennes, 35203, France

    Contact

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59020, France

    Contact

  • Gustave Roussy

    RECRUITING

    Villejuif, Val de Marne, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Robert Debré

    RECRUITING

    Paris, 75019, France

    Contact

  • Institut Curie

    RECRUITING

    Paris, 75248, France

    Contact