Amazonian tree oil may soothe radiation mouth sores in cancer patients

NCT ID NCT05308732

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests whether a mouthwash made from copaiba, a natural oil from the Amazon, can safely help prevent and treat painful mouth sores caused by radiation therapy in 20 adults with head and neck cancer. Researchers will find the highest safe dose and measure pain levels. The goal is to offer an alternative when standard laser therapy cannot be used on tumor areas.

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Conditions

The condition(s) this trial relates to.

head and neck neoplasm Head and Neck Neoplasms oral cavity cancer stomatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Nacional de Cancer

    Rio de Janeiro, Rio de Janeiro, 20231-050, Brazil