Can a common amino acid boost heart function in failure patients?
NCT ID NCT07394270
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether adding L-arginine, a natural amino acid, to standard heart failure treatment improves heart function and symptoms. Researchers will enroll 200 stable heart failure patients with low ejection fraction (under 40%). Participants will receive either L-arginine powder or a placebo twice daily for a set period, and the study will measure changes in heart strain, symptoms, and exercise ability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
L-arginine powder
What this could lead to
If it works, this could point toward a simple, low-cost supplement to improve heart function and reduce symptoms in heart failure patients.
What could go wrong
This is an early phase 2 trial with only 200 participants, so results may not be conclusive. L-arginine may cause side effects or show no benefit over placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ain Shams University
Cairo, Egypt