New drug Kylo-12 enters first human safety trial for high cholesterol fats

NCT ID NCT06783881

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tests a new drug called Kylo-12 in 50 healthy volunteers to see if it is safe and how the body processes it. The drug aims to lower high triglycerides, a type of fat in the blood linked to heart problems. Participants receive either a single shot of Kylo-12 or a placebo, and researchers monitor for side effects and measure drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Kylo-12

What this could lead to

If successful, this could lead to a new treatment option for people with high triglycerides, a condition that raises heart disease risk.

What could go wrong

This is a very early Phase 1 trial in only 50 healthy people, so it is not yet known if Kylo-12 works or is safe long-term. Side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERTRIGLYCERIDEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hypertriglyceridemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chengdu Xinhua Hospital

    Chengdu, Sichuan, 610000, China