Knee replacement showdown: which alignment method wins?

NCT ID NCT06617871

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods of knee replacement surgery: traditional mechanical alignment (MA) and newer kinematic alignment (KA) that mimics the knee's natural position. About 95 adults with knee arthritis will be randomly assigned to one method and followed for 6 weeks. The goal is to see which approach leads to better patient-reported knee function and comfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for KNEE OSTEOARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

arthropathy osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern Medicine

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••