Knee replacement study tests new alignment method, but stalls after just one patient

NCT ID NCT06617338

Terminated Knowledge-focused Sponsor: University of Louisville Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if using a patient's healthy knee as a guide for aligning a new knee joint during replacement surgery leads to better results than the standard method. Researchers planned to compare two groups of people with arthritis in one knee, using CT scans to plan the surgery. However, the study was stopped early after only one person enrolled, so no meaningful conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CT scan
What this could lead to: If successful, this approach could help surgeons better align knee replacements, potentially improving function and satisfaction.
What could go wrong: The study was terminated early with only 1 participant, so no reliable conclusions can be drawn. The approach may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS (OA) OF THE KNEE

Contacts and locations

Locations

UofL Health

Louisville, Kentucky, 40202, United States

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