New knee pain treatment approach tested in pilot study

NCT ID NCT07674082

Not yet recruiting Symptom relief Sponsor: Lawson Research Institute of St. Joseph's Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This pilot study compares two standard-of-care radiofrequency ablation (RFA) techniques for chronic knee pain caused by osteoarthritis. Adults already scheduled for knee RFA are randomly assigned to receive either a standard 3-target or a novel 6-target nerve ablation protocol. The main goal is to see if a larger trial comparing these approaches is feasible and safe. Participants complete pain and function questionnaires for up to 12 months after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiofrequency ablation
What this could lead to: If successful, this study could pave the way for a larger trial that identifies a more effective RFA protocol for lasting knee pain relief.
What could go wrong: This is a small pilot study with only 24 participants, so results may not apply to everyone. The novel 6-target technique may not provide better pain relief and could carry similar risks as the standard procedure.

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis susceptibility 6 osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

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Other studies related to the condition(s) this trial covers.