New patch zaps knee pain without drugs?

NCT ID NCT07351981

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a special patch that delivers pulsed radiofrequency energy can reduce knee pain in people with osteoarthritis. Fifty adults aged 40-75 with chronic knee pain will receive either the real patch or a sham device. Researchers will measure pain and function over 6 months to see if the treatment works better than a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcutaneous pulsed radiofrequency (PRF) patch

What this could lead to

If it works, this could offer a non-invasive, drug-free option for easing chronic knee pain from osteoarthritis.

What could go wrong

This is a small, early-stage trial with only 50 participants. The sham control may show similar results, and long-term benefits are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aretaieion University Hospital

    Athens, Greece