New knee pain drug shows promise in early trial

NCT ID NCT05025787

Completed Symptom relief Sponsor: Maurizio Fava, MD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called CNTX-6970 in 55 adults aged 40-90 with moderate to severe knee osteoarthritis pain. The goal was to see if the drug safely reduces pain better than a placebo over 24 weeks. Participants used a mobile app to report their pain levels.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Center for Clinical Research

Winston-Salem, North Carolina, 27103, United States
Healthcare Research Network

Hazelwood, Missouri, 63042, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
M&M Clinical Trials

Miami, Florida, 33185, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
New York University Langone Health

New York, New York, 10016, United States
UTsouthwestern Medical Center

Dallas, Texas, 75390, United States
University of California San Diego

La Jolla, California, 92037, United States
University of California- Davis

Sacramento, California, 95817, United States
University of Florida

Gainesville, Florida, 32611, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19146, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15206, United States
University of Rochester

Rochester, New York, 14618, United States
University of Washington

Seattle, Washington, 98195, United States
University of Wisconsin- Madison

Madison, Wisconsin, 53715-1218, United States

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