Can your Doctor's style predict knee pain relief? new study investigates

NCT ID NCT06574191

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how a person's background and their clinic visit affect knee osteoarthritis pain relief using topical diclofenac gel. 220 adults aged 50+ with knee OA will apply the gel for 8 weeks and answer questions about their pain. Researchers will also analyze blood samples and video recordings of visits to find patterns that predict who responds best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Topical diclofenac gel 1%
What this could lead to
If successful, this could help doctors personalize knee osteoarthritis treatment by identifying which patients benefit most from topical diclofenac gel.
What could go wrong
This is an early-stage observational study, not a large-scale trial. Results may not apply to all patients, and the gel may not work for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California Davis Health

    RECRUITING

    Sacramento, California, 95817, United States

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