Obesity linked to higher knee implant infection risk in massive registry study
NCT ID NCT07398742
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study used Danish national health records to compare infection rates after total knee replacement in obese (BMI ≥30) versus non-obese patients. Researchers analyzed data from over 100,000 adults who had knee replacement for osteoarthritis between 2011 and 2021. They looked at how many needed revision surgery due to infection within two years, and what types of bacteria caused those infections. The goal is to help tailor preventive antibiotics and infection management for obese patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors choose better antibiotics and preventive measures for obese patients undergoing knee replacement.
What could go wrong
This is an observational study using existing records, not a controlled trial. It can show links but cannot prove cause and effect.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Orthopedic surgery and traumatology, Bispebjerg Hospital, Copenhagen, Denmark
Copenhagen NV, 2400, Denmark