New hope for young kidney transplant patients: safer drug combo tested
NCT ID NCT06055608
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a combination of belatacept and sirolimus works better than the standard drugs tacrolimus and MMF in children aged 13-20 who receive a kidney transplant. The goal is to reduce the risk of organ rejection and protect kidney function. Participants are randomly assigned to one of the two drug groups and followed for 12-24 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ann and Robert H. Lurie Children's Hospital of Chicago (Site #: 71016)
RECRUITINGChicago, Illinois, 60611, United States
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Boston Children's Hospital (Site #: 71001)
RECRUITINGBoston, Massachusetts, 02215, United States
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Cedars-Sinai Medical Center (Site #: 71026)
RECRUITINGLos Angeles, California, 90048, United States
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Children's Hospital of Colorado (Site #: 71019)
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital of Los Angeles (Site #: 71036)
NOT_YET_RECRUITINGLos Angeles, California, 90027, United States
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Children's Hospital of Philadelphia (Site #: 71091)
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Children's National Medical Center (Site #: 71039)
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center (Site #: 71017)
RECRUITINGCincinnati, Ohio, 45229, United States
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Duke University (Site #: 71033)
RECRUITINGDurham, North Carolina, 27710, United States
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Helen DeVos Children's Hospital (Site #: 71035)
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Johns Hopkins Children's Center (Site #: 71025)
RECRUITINGBaltimore, Maryland, 21287, United States
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Mattel Children's Hospital, UCLA (Site #: 71012)
RECRUITINGLos Angeles, California, 90095, United States
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Nemours Children's Health (Site #: 71042)
RECRUITINGWilmington, Delaware, 19803, United States
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New York Medical College/Boston Children's Health Physicians
NOT_YET_RECRUITINGWestchester, New York, 10461, United States
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Seattle Children's Hospital (Site #: 71041)
RECRUITINGSeattle, Washington, 98105, United States
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Texas Children's Hospital (Baylor) (Site #: 71005)
RECRUITINGHouston, Texas, 77030, United States
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UCSD Rady Children's Hospital (Site #: 71037)
RECRUITINGSan Diego, California, 92123, United States
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UPMC Children's Hospital of Pittsburgh (Site #: 71008)
RECRUITINGPittsburgh, Pennsylvania, 15224, United States
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University of Alabama at Birmingham (Site # 71038)
RECRUITINGBirmingham, Alabama, 35233, United States
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Washington University/St. Louis Children's Hospital (Site #: 71006)
RECRUITINGSt Louis, Missouri, 63110, United States
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