Scientists probe Ketamine's Fast-Acting depression relief in brain receptor study

NCT ID NCT03973268

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 27 times

Summary

This study looks at how ketamine quickly improves depression symptoms in adults with treatment-resistant major depression. Researchers want to see if a specific brain receptor (AMPA) is involved. Participants will stay at the hospital for 5 weeks, take ketamine and a study drug or placebo, and undergo brain scans and tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.