Could ketamine make shock therapy safer and more effective for depression?

NCT ID NCT07088380

First seen Jun 05, 2026 · Last updated Jun 15, 2026 · Updated 3 times

Summary

This study tests whether adding ketamine to electroconvulsive therapy (ECT) helps people with severe, treatment-resistant depression feel better and have fewer memory problems. Thirty hospitalized adults will receive either ketamine or a placebo during three ECT sessions. The goal is to see if the combination improves mood and reduces suicidal thoughts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Ospedale San Raffaele Turro

    RECRUITING

    Milan, 20127, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.