Università Vita-salute San Raffaele

This study tests whether pirfenidone, a drug already used for a different lung disease, can prevent scarring in patients with severe acute respiratory distress syndrome (ARDS). About 130 people on ventilators will receive either pirfenidone or a placebo through a feeding tube. Th…

This study tests if adding the drug landiolol to the fluid that protects the heart during mitral valve surgery can reduce a serious complication called low cardiac output syndrome, where the heart struggles to pump enough blood after surgery. About 1500 adults having elective mit…

This study is testing a new blood test that looks at tiny particles called exosomes and their microRNA content, analyzed by machine learning, to detect pancreatic cancer early. It involves 600 people at high risk due to family history or pancreatic cysts. The goal is to see if th…

This study tests whether a special PET/MRI scan can accurately detect if breast cancer has spread to lymph nodes in the armpit, potentially replacing the need for surgical removal of those nodes. About 119 women with certain types of breast cancer (luminal A or lobular) will get …

This phase 3 trial tests whether adding a low dose of ketamine to electroconvulsive therapy (ECT) can better relieve depression and reduce memory problems in people with treatment-resistant major depressive disorder. Thirty hospitalized adults will receive either ketamine or a pl…

This observational study will track 300 adults with advanced heart failure to see how well they follow a four-medication treatment plan. Researchers will also measure quality of life using standard questionnaires. The goal is to understand real-world adherence and identify areas …

This study is collecting medical information and biological samples from up to 6,000 people with COVID-19. Researchers want to find out which factors predict severe illness, death, or response to treatment. The goal is to better understand the disease and help guide future care.

This study tests a new portable CPAP device designed to help people with sudden breathing failure before they reach the hospital. Researchers want to see if the device is easy enough for non-medical people to use correctly. The study involves 50 participants: healthy older adults…