No-Surgery weight loss: new stitch procedure tested in 186 people

NCT ID NCT06272201

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a minimally invasive procedure called POSE2.0 for weight loss in 186 adults with obesity. The procedure uses stitches placed in the stomach without any incisions, combined with a diet and exercise program. Researchers will compare weight loss and safety between those who get the procedure plus lifestyle changes and those who only follow the diet and exercise program.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

POSE2.0 procedure with g-Cath EZ Delivery Catheter and Snowshoe Suture Anchors

What this could lead to

If successful, this could offer a less invasive weight loss option for people with obesity who haven't had success with diet and exercise alone.

What could go wrong

This is a pivotal study, but results may not apply to everyone. The procedure carries risks like any medical intervention, and long-term weight loss success is not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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  • Contact

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