In-Clinic polyp removal could replace costly sinus surgery

NCT ID NCT02975310

Recruiting now Symptom relief Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways to treat chronic sinusitis with nasal polyps: a new in-clinic procedure done under local anesthesia versus standard sinus surgery in an operating room. Researchers will enroll 140 adults to see if the in-clinic approach controls symptoms just as well, while being faster, cheaper, and easier to access. If successful, it could become the new standard of care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: endoscopic polypectomy in clinic (polyp removal using a microdebrider under local anesthesia)
What this could lead to: If it works, this could replace expensive sinus surgery with a cheaper, quicker in-clinic procedure for many patients with nasal polyps.
What could go wrong: This is a mid-stage trial with 140 participants, so results may not apply to everyone. The in-clinic procedure may not control symptoms as well as surgery in the long run.

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Conditions

The condition(s) this trial relates to.

nasal cavity polyp sinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASAL POLYPS SINUSITIS

Contacts and locations

Locations

McGill University Health Center
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Ottawa Hospital Research Institute
RECRUITING

Ottawa, Ontario, K1Y 1J8, Canada
St. Joseph's Hospital London
RECRUITING

London, Ontario, N6A 4V2, Canada
Vancouver General Hospital
RECRUITING

Vancouver, British Columbia, Canada

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