Could a simple shot ease achy hands? new trial investigates

NCT ID NCT07371572

Recruiting now Symptom relief Sponsor: Sint Maartenskliniek Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether a single steroid injection (methylprednisolone) can reduce pain in people with hand osteoarthritis. 212 participants will receive either a high dose, a low dose, or a placebo, and report their pain after 4 weeks. After 16 weeks, everyone can receive the injection on demand for up to 48 weeks. The goal is to see if this treatment offers safe, effective pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: methylprednisolone (a steroid injection)
What this could lead to: If it works, this could provide a simple, occasional injection to reduce hand pain for people with osteoarthritis.
What could go wrong: This is a Phase 3 trial, but it only measures pain after one injection. The effect may be short-lived, and steroids have risks like joint damage with repeated use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis susceptibility 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HAND OSTEOARTHRITIS

Contacts and locations

Locations

Sint Maartenskliniek
RECRUITING

Ubbergen, Gelderland, 6574 NA, Netherlands

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