Osteoarthritis susceptibility 2

This study tests if a procedure called arterial embolization using Lipiodol is safe for people with painful hand osteoarthritis that hasn't improved with standard treatments. Fifteen participants will receive the procedure and be followed for 6 months to track side effects, pain …

This study tests whether Multiprofen-CC cream, applied three times daily, reduces pain in adults with hand osteoarthritis. Forty-two participants will use both the active cream and a placebo for two weeks each, in random order. Researchers will measure pain, hand function, and si…

This study compares two treatments for hand and wrist osteoarthritis pain: low-dose radiotherapy and corticosteroid injections. Researchers want to see which works better at reducing pain and improving hand function. The study involves 165 adults aged 50 and older with moderate t…

This Phase 3 trial tests whether a single steroid injection (methylprednisolone) can reduce pain in people with hand osteoarthritis. 212 participants will receive either a high dose, a low dose, or a placebo, and report their pain after 4 weeks. After 16 weeks, everyone can recei…

This study aims to better understand and treat people with certain inherited metabolic or genetic disorders. Researchers will use standard medical tests like blood work and imaging to diagnose and care for participants, who may also join other related studies. The goal is to expa…

This study is testing a new online platform called Nest for young adults aged 18-39 who have had genetic testing for cancer risk. The platform gives both patients and their doctors access to updated information about genetic findings. Researchers want to see if the tool is easy t…

This study from St. Jude Children's Research Hospital looks at how parents and children (ages 10-24) talk about the child's genetic risk for cancer. The goal is to understand what helps or hinders these conversations, so doctors can create better education programs. The study wil…

This study follows 150 people with early hand osteoarthritis to see if imaging techniques like ultrasound and MRI can predict which patients will get worse over time. Researchers will track joint changes on X-rays and look for links to symptoms like pain and swelling. The goal is…

This study compares two ways to provide pre-test genetic counseling to people at high risk for hereditary cancers: a chatbot (Genetic Information Assistant) versus a live telegenetics session with a genetic counselor. About 96 participants will be randomly assigned to one method,…