Can rewriting bad memories ease depression? small study tests new therapy in GP offices
NCT ID NCT07362511
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a therapy called Imagery Rescripting (ImRs) can help reduce depressive symptoms when delivered by mental health assistants in primary care. Twelve adults with depression will wait 2-4 weeks, then receive 5 sessions of ImRs over 10 weeks, where they work with a therapist to change negative memories into more positive ones. Researchers will measure changes in depression severity, self-esteem, and core beliefs up to six months after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Imagery Rescripting (ImRs) - a therapy where patients change negative memories into more positive ones with a therapist's help
What this could lead to
If it works, this could offer a brief, accessible therapy for depression within primary care, reducing the need for specialist referrals.
What could go wrong
This is a very small early study with only 12 participants, no control group, and no blinding, so results may not apply broadly. The therapy may not work for everyone or effects may not last.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UvA Huisartsen
RECRUITINGAmsterdam, North Holland, 1018VZ, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••