New shorter radiation course aims to ease sarcoma treatment for seniors

NCT ID NCT06022159

Recruiting now Disease control Sponsor: Institut Claudius Regaud Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a shorter, higher-dose radiation therapy given over one week before surgery for soft tissue sarcoma in patients aged 70+ or those 65+ who are considered fragile. The goal is to see if this approach reduces major wound complications after surgery. About 48 participants will receive the radiation followed by surgery and be monitored for up to 3 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hypofractionated radiation therapy (IMRT)
What this could lead to: If successful, this shorter radiation course could become a standard option for older or fragile sarcoma patients, reducing treatment burden and wound healing problems.
What could go wrong: This is a small, early-phase study with only 48 participants and no comparison group. The shorter radiation schedule may still cause wound complications or fail to control the cancer as well as standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOFT TISSUE SARCOMA

Contacts and locations

Locations

Centre Leon Berard
RECRUITING

Lyon, France
Centre Oscar Lambret
RECRUITING

Lille, France
Chu de Limoges
RECRUITING

Limoges, France
Chu de Poitiers
RECRUITING

Poitiers, France
Chu de Toulouse
RECRUITING

Toulouse, France
IUCT-O
RECRUITING

Toulouse, France
Institut Bergonie
RECRUITING

Bordeaux, France
Institut Curie
RECRUITING

Paris, France
Institut Gustave Roussy
RECRUITING

Villejuif, France
Institut Regional Du Cancer de Montpellier
RECRUITING

Montpellier, France
Institut de Cancerologie de L'Ouest
RECRUITING

Saint-Herblain, France

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