Could a breath of CO2 save Stroke-Damaged brain tissue?
NCT ID NCT05051397
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether raising carbon dioxide levels slightly during general anesthesia can improve blood flow to the brain before clot removal in stroke patients. Fifty adults with large-vessel stroke will be randomly assigned to either normal or moderately high carbon dioxide levels during the procedure. The goal is to see if this simple gas adjustment helps keep brain tissue alive until the clot is removed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- carbon dioxide
- What this could lead to
- If it works, this could point toward a simple way to protect the brain during stroke treatment by using carbon dioxide to boost blood flow.
- What could go wrong
- This is a small, early-phase trial with only 50 participants. The approach may not improve outcomes or could cause harm if carbon dioxide levels are not carefully managed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU
RECRUITINGClermont-Ferrand, 63000, France
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Other studies related to the condition(s) this trial covers.
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