THROMBECTOMY

This study tests whether the drug sivelestat sodium, given alongside standard clot-removal surgery, can help people recover better after a major stroke. The trial will include 868 adults aged 18-80 with large-vessel blockage in the front part of the brain. The goal is to see if t…

This study looks at how well and how safely the Tigertriever device works to remove blood clots from large brain vessels in people having an ischemic stroke. About 150 adults will be treated within 8 hours of their first symptoms. The goal is to restore blood flow and improve rec…

This study compares a procedure to remove blood clots (endovascular therapy) with standard medical care for people who have had a mild stroke caused by a blockage in a large brain artery. About 264 adults with mild symptoms (NIHSS score 2-5) will be enrolled within 24 hours of st…

This study tests whether giving the steroid methylprednisolone right after a stroke clot removal procedure can help patients recover better. About 210 adults who had a major stroke from a blocked artery in the brain will be randomly assigned to receive either the steroid or a pla…

This study tests whether raising carbon dioxide levels slightly during general anesthesia can improve blood flow to the brain before clot removal in stroke patients. Fifty adults with large-vessel stroke will be randomly assigned to either normal or moderately high carbon dioxide…

This study looks at why about half of stroke patients don't recover well even after doctors successfully remove a blood clot from their brain. Researchers will use special MRI scans to measure blood flow changes in the brain at 3 days, 7 days, and 90 days after the procedure. The…

This study looks at how the immune system and blood clotting change in the first day after a stroke treated with a clot-removal procedure called thrombectomy. Researchers will collect blood samples from 1,200 participants to find markers that might predict how well people recover…