New drug could boost stroke recovery by calming brain inflammation

NCT ID NCT07552610

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether the drug sivelestat sodium, given alongside standard clot-removal surgery, can help people recover better after a major stroke. The trial will include 868 adults aged 18-80 with large-vessel blockage in the front part of the brain. The goal is to see if the drug reduces inflammation and leads to less disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sivelestat sodium

What this could lead to

If it works, this could reduce disability after stroke by preventing further brain damage from inflammation.

What could go wrong

This is an early-stage trial with no phase specified, so results are uncertain. The drug may not improve outcomes or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gaomi People's Hospital

    RECRUITING

    Weifang, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xuanwu Hospital, Capital Medical University.

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••