New drug could boost stroke recovery by calming brain inflammation
NCT ID NCT07552610
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether the drug sivelestat sodium, given alongside standard clot-removal surgery, can help people recover better after a major stroke. The trial will include 868 adults aged 18-80 with large-vessel blockage in the front part of the brain. The goal is to see if the drug reduces inflammation and leads to less disability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sivelestat sodium
- What this could lead to
- If it works, this could reduce disability after stroke by preventing further brain damage from inflammation.
- What could go wrong
- This is an early-stage trial with no phase specified, so results are uncertain. The drug may not improve outcomes or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Gaomi People's Hospital
RECRUITINGWeifang, Shandong, China
-
Xuanwu Hospital, Capital Medical University.
RECRUITINGBeijing, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a drug boost brain recovery after stroke?
- Can a blood Clot's inflammation predict stroke recovery?
- Can a new infusion drug boost stroke recovery?
- Can removing clots from tiny brain arteries boost stroke recovery?
- Could vague stroke symptoms delay lifesaving treatment?