New obesity drug HM15275 enters Mid-Stage trial
NCT ID NCT07205900
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This phase 2 study tests an experimental drug called HM15275 for weight loss in 267 adults who are obese or overweight but do not have diabetes. Participants receive either the drug or a placebo as a weekly injection for 36 weeks. The main goal is to see how much body weight changes from the start to the end of treatment.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- HM15275 (injectable drug)
- What this could lead to
- If successful, this could lead to a new weight-loss medication for people with obesity or overweight.
- What could go wrong
- This is an early phase 2 trial with only 267 people, so results may not apply to everyone. The drug may cause side effects or fail to show meaningful weight loss compared to placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Accellacare of Bristol-PAC of Tennessee
Bristol, Tennessee, 37620, United States
-
Accellacare of Cary - Cary Medical Group
Cary, North Carolina, 27511, United States
-
Accellacare of Charleston
Mt. Pleasant, South Carolina, 29464, United States
-
Accellacare of Duly - Duly Oak Lawn
Oak Lawn, Illinois, 60453, United States
-
Accellacare of Hickory
Hickory, North Carolina, 28601, United States
-
Accellacare of McFarland
Ames, Iowa, 50010, United States
-
Accellacare of Piedmont - Piedmont HealthCare
Statesville, North Carolina, 28626, United States
-
Accellacare of Wilmington, LLC
Wilmington, North Carolina, 28401, United States
-
Accellacare of Winston Salem
Winston-Salem, North Carolina, 27103, United States
-
Bristol-Internal Medicine and Pediatric Associates of Bristol, P.C.
Bristol, Tennessee, 37620, United States
-
ProSciento Inc
Chula Vista, California, 91911, United States
-
Raleigh Medical Group, P.A.
Raleigh, North Carolina, 27609, United States
-
Texas Clinical Research Institute
Arlington, Texas, 76012, United States
-
Velocity Clinical Research, Dallas
Dallas, Texas, 75230, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new stomach and gut bypass surgery tackle obesity and diabetes?
- Can a Two-Drug combo tip the scales against obesity?
- Can Weight-Loss surgery change how medications work?
- Coffee grounds probiotic could reshape gut health and fight inflammation
- Can shedding pounds reboot the Heart's exercise engine?
- Can stomach surgery alter how painkillers work?