New obesity drug HM15275 enters Mid-Stage trial

NCT ID NCT07205900

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tests an experimental drug called HM15275 for weight loss in 267 adults who are obese or overweight but do not have diabetes. Participants receive either the drug or a placebo as a weekly injection for 36 weeks. The main goal is to see how much body weight changes from the start to the end of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HM15275 (injectable drug)

What this could lead to

If successful, this could lead to a new weight-loss medication for people with obesity or overweight.

What could go wrong

This is an early phase 2 trial with only 267 people, so results may not apply to everyone. The drug may cause side effects or fail to show meaningful weight loss compared to placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Accellacare of Bristol-PAC of Tennessee

    Bristol, Tennessee, 37620, United States

  • Accellacare of Cary - Cary Medical Group

    Cary, North Carolina, 27511, United States

  • Accellacare of Charleston

    Mt. Pleasant, South Carolina, 29464, United States

  • Accellacare of Duly - Duly Oak Lawn

    Oak Lawn, Illinois, 60453, United States

  • Accellacare of Hickory

    Hickory, North Carolina, 28601, United States

  • Accellacare of McFarland

    Ames, Iowa, 50010, United States

  • Accellacare of Piedmont - Piedmont HealthCare

    Statesville, North Carolina, 28626, United States

  • Accellacare of Wilmington, LLC

    Wilmington, North Carolina, 28401, United States

  • Accellacare of Winston Salem

    Winston-Salem, North Carolina, 27103, United States

  • Bristol-Internal Medicine and Pediatric Associates of Bristol, P.C.

    Bristol, Tennessee, 37620, United States

  • ProSciento Inc

    Chula Vista, California, 91911, United States

  • Raleigh Medical Group, P.A.

    Raleigh, North Carolina, 27609, United States

  • Texas Clinical Research Institute

    Arlington, Texas, 76012, United States

  • Velocity Clinical Research, Dallas

    Dallas, Texas, 75230, United States