New program aims to tackle HIV stigma and depression in teens

NCT ID NCT07221201

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests a program called Project YES+ for youth aged 15-21 living with HIV in Zambia. The program combines peer mentoring with mental health support to reduce stigma, violence, and depression. Researchers will enroll 400 participants to see if the program is feasible and acceptable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Project YES+ behavioral intervention (peer mentoring and WHO-endorsed mental health approaches)

What this could lead to

If successful, this could provide a scalable way to improve HIV medication adherence and viral suppression among young people by addressing stigma and mental health.

What could go wrong

This is a small pilot study focused on feasibility, not effectiveness. Results may not apply to other regions or populations, and the intervention requires significant community support.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS anxiety anxiety disorder HIV infectious disease Psychological Well-Being Social Stigma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arthur Davison Children's Hospital

    Ndola, Copperbelt, Zambia