New oxygen method may prevent dangerous drops during endoscopy

NCT ID NCT06610461

Completed Symptom relief Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving high-flow nasal oxygen (HFNO) during upper GI endoscopy in high-risk patients (e.g., those with sleep apnea or obesity) reduces the risk of blood oxygen levels falling too low. 180 patients were randomly assigned to receive either HFNO or standard oxygen via face mask or nasal cannula. The goal was to see if HFNO could prevent the need for emergency airway maneuvers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-flow nasal oxygen (HFNO) delivered via a device
What this could lead to: If it works, this could provide a safer way to give sedation during upper GI endoscopy in high-risk patients, reducing the need for emergency airway procedures.
What could go wrong: This is a small, completed study (180 patients) and results may not apply to all settings. The intervention may not significantly reduce oxygen drops or could cause discomfort.

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Conditions

The condition(s) this trial relates to.

Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOXEMIA DURING SURGERY

Contacts and locations

Locations

Anesthesia, Critical Care and Pain Medicine Department at Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States

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