New oxygen method may prevent dangerous drops during endoscopy

NCT ID NCT06610461

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving high-flow nasal oxygen (HFNO) during upper GI endoscopy in high-risk patients (e.g., those with sleep apnea or obesity) reduces the risk of blood oxygen levels falling too low. 180 patients were randomly assigned to receive either HFNO or standard oxygen via face mask or nasal cannula. The goal was to see if HFNO could prevent the need for emergency airway maneuvers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High-flow nasal oxygen (HFNO) delivered via a device

What this could lead to

If it works, this could provide a safer way to give sedation during upper GI endoscopy in high-risk patients, reducing the need for emergency airway procedures.

What could go wrong

This is a small, completed study (180 patients) and results may not apply to all settings. The intervention may not significantly reduce oxygen drops or could cause discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anesthesia, Critical Care and Pain Medicine Department at Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States