New pain drug may reduce breathing risks during routine scopes

NCT ID NCT07187765

Completed Symptom relief Sponsor: Shiyou Wei Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two painkillers—oliceridine and sufentanil—given alongside propofol sedation during gastrointestinal endoscopy. The goal was to see if oliceridine causes fewer episodes of low blood oxygen (hypoxemia) than the standard drug. Over 500 adults participated, and researchers tracked oxygen levels throughout the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oliceridine (TRV130)
What this could lead to: If it works, oliceridine could become a safer painkiller option for routine endoscopic procedures, reducing the risk of low oxygen levels during sedation.
What could go wrong: This is a single-center, completed trial with 508 participants. The results may not apply to all patients or settings, and oliceridine may not prove safer than the standard drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GASTROINTESTINAL ENDOSCOPY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL ENDOSCOPY HYPOXEMIA DURING SURGERY

Contacts and locations

Locations

Tianmen First People's Hospital

Tianmen, Hubei, 431700, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.