New pain drug may reduce breathing risks during routine scopes
NCT ID NCT07187765
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two painkillers—oliceridine and sufentanil—given alongside propofol sedation during gastrointestinal endoscopy. The goal was to see if oliceridine causes fewer episodes of low blood oxygen (hypoxemia) than the standard drug. Over 500 adults participated, and researchers tracked oxygen levels throughout the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oliceridine (TRV130)
What this could lead to
If it works, oliceridine could become a safer painkiller option for routine endoscopic procedures, reducing the risk of low oxygen levels during sedation.
What could go wrong
This is a single-center, completed trial with 508 participants. The results may not apply to all patients or settings, and oliceridine may not prove safer than the standard drug.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tianmen First People's Hospital
Tianmen, Hubei, 431700, China