Heart transplant patients may soon take just one pill a day
NCT ID NCT03373227
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a once-daily version of the anti-rejection drug tacrolimus (Envarsus) works as well as the standard twice-daily version (Prograf) in heart transplant recipients. Fifty adults who had a heart-only transplant were enrolled. The goal was to see if the easier once-daily dosing could improve medication compliance and reduce the risk of organ rejection or graft failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tacrolimus (Envarsus and Prograf)
- What this could lead to
- If successful, this could show that a once-daily pill is as effective as twice-daily dosing, making it easier for heart transplant patients to stick to their medication schedule and potentially reduce rejection risks.
- What could go wrong
- This is a small, early-phase study with only 50 participants, so results may not apply to all patients. The study is also open-label, meaning both patients and doctors know which drug is given, which can introduce bias.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Baylor University Medical Center
Dallas, Texas, 75246, United States
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