Blood test may replace painful heart biopsies for transplant patients

NCT ID NCT07531784

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a blood test that measures donor DNA can detect rejection in heart transplant patients. Researchers will compare the test results with standard heart biopsies in 120 adults across Sweden. If the test works well, it could offer a less invasive way to monitor for rejection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

donor-derived cell-free DNA blood test

What this could lead to

If successful, this blood test could replace some invasive heart biopsies, making rejection monitoring safer and easier for transplant patients.

What could go wrong

This is an observational study, not a treatment trial. The test may not be accurate enough to replace biopsies, and results may vary between patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Karolinska University Hospital

    RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••