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Heart transplant breakthrough: keeping donor hearts beating during transport could save more lives

NCT ID NCT03991923

Ongoing Disease control Sponsor: XVIVO Perfusion Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new method of preserving donor hearts (keeping them warm and beating with blood flow) to the standard cold storage method. The goal is to see if the new approach leads to better heart function and fewer complications in the first month and year after transplant. About 230 adult heart transplant recipients will take part across multiple centers.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART TRANSPLANTATION

Contacts and locations

Locations

  • Allgemeines Krankenhaus der Stadt Wien

    Vienna, Austria

  • Azienda osedalaria di Padova

    Padova, Padova PD, 35121, Italy

  • Deutschen Herzzentrum Berlin

    Berlin, Brandenburg, 13353, Germany

  • Freeman Hospital

    Newcastle, Newcastle Upon Tyne, NE77DN, United Kingdom

  • Hannover Medical School

    Hanover, Germany

  • Hospital Puerto de Hierro

    Madrid, Majadahonda Madrid, 28222, Spain

  • Hôpital Bichat Claude-Bernard

    Paris, France

  • Institut de cardiologie, Chirurgie thoracique et cardiovasculaire La Pitié Salpetrière

    Paris, Paris Cedex, 75651, France

  • Klinikum der Universität München

    München, Bavaria, 81377, Germany

  • Queen Elisabeth Hospital

    Birmingham, B152TH, United Kingdom

  • Royal Papworth Hospital

    Cambridge, United Kingdom

  • Sahlgrenska University Hospital

    Gothenburg, Västra Götalands Regionen, 412 34, Sweden

  • UZ Leuven

    Leuven, Flemish Brabant, 3000, Belgium

  • Universitätsklinik der Ruhr-Universität Bochum

    Bad Oeynhausen, Germany

  • Universitätsklinikum Düsseldorf

    Düsseldorf, Germany

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