Nerve zapper offers hope for chronic headache sufferers

NCT ID NCT07553533

ENROLLING_BY_INVITATION Symptom relief Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a 60-day nerve stimulation device placed near the back of the head can help people with stubborn headaches. Researchers will track pain levels, daily function, and how often participants need emergency care. About 300 adults with various headache types will take part, and the device is used as part of their normal medical care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: occipital nerve peripheral nerve stimulation (PNS) device
What this could lead to: If successful, this could offer a temporary, non-drug option for people with hard-to-treat headaches, reducing pain and emergency visits.
What could go wrong: This is an observational study, not a controlled trial, so results may be less reliable. The treatment is temporary (60 days) and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cluster headache syndrome Headache headache disorder migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEADACHE

Contacts and locations

Locations

Yale

New Haven, Connecticut, 06520, United States
Yale

Old Saybrook, Connecticut, 06475, United States

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