New obesity drug HDM1005 enters Mid-Stage trial

NCT ID NCT06886126

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial is testing an investigational drug called HDM1005 for weight loss in 240 adults with obesity who do not have diabetes. Participants receive weekly injections of either the drug or a placebo for 22 weeks. The main goal is to see how much body weight they lose and whether the drug is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HDM1005 injection

What this could lead to

If successful, this could lead to a new weight-loss treatment for people with obesity who do not have diabetes.

What could go wrong

This is an early Phase 2 trial with only 240 participants, so results may not apply to everyone. The drug may cause side effects or fail to show meaningful weight loss compared to placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, China

    Contact