Could Hands-Only CPR be just as good as standard CPR?

NCT ID NCT03981107

First seen May 11, 2026 · Last updated Jun 22, 2026 · Updated 5 times

Summary

This study compares two types of CPR for people who have a cardiac arrest outside a hospital: hands-only CPR (chest compressions without rescue breaths) versus standard CPR (compressions plus rescue breaths). The trial will include over 3,000 adults whose cardiac arrest is witnessed and who have a bystander with prior CPR training. The goal is to see if hands-only CPR is at least as effective as standard CPR at helping people survive for 30 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AREU, Agenzia Regionale Emergenza Urgenza

    RECRUITING

    Bergamo, Italy

  • SOS Alarm AB

    RECRUITING

    Stockholm, Sweden

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Chest compression only CPR (hands-only CPR)

What this could lead to

If hands-only CPR works as well as standard CPR, it could simplify training and encourage more bystanders to act, potentially saving more lives from cardiac arrest.

What could go wrong

This is a large trial, but it only includes trained bystanders and witnessed arrests. Results may not apply to all situations, and hands-only CPR might be less effective for certain causes of cardiac arrest.

Conditions

The condition(s) this trial relates to.

cardiac arrest Out-of-Hospital Cardiac Arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.