New stomach bug treatment could be simpler and smarter

NCT ID NCT07439445

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a 14-day treatment for Helicobacter pylori, a stomach infection that can cause ulcers and cancer. The treatment uses two drugs, vonoprazan and clarithromycin, and is guided by a stool test to check if the bacteria are resistant to clarithromycin. The goal is to see if this simpler approach works well and has fewer side effects. The study involves 70 adults who have not been treated for H. pylori before.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vonoprazan and clarithromycin

What this could lead to

If successful, this could offer a simpler, more effective first-line treatment for H. pylori infection, reducing the risk of stomach ulcers and cancer.

What could go wrong

This is a small, early-phase study with only 70 participants, so results may not apply to everyone. The treatment may fail if the bacteria are resistant to clarithromycin, and side effects like nausea or diarrhea are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••