DNA-Guided heart therapy could prevent thousands of heart attacks

NCT ID NCT03783351

First seen Jan 08, 2026 · Last updated Jun 17, 2026 · Updated 28 times

Summary

This study looked at whether using a person's genetic information to choose their blood thinner medication after getting a heart stent can reduce the risk of heart attacks, strokes, and death. About 4,000 people with heart disease were given either clopidogrel or ticagrelor based on their CYP2C19 gene type. The goal was to see if this personalized approach is safer and more effective than standard care.

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Contacts and locations

Locations

  • Beijing Anzhen Hospital

    Beijing, Beijing Municipality, 100029, China

  • Beijing Chaoyang Hospital

    Beijing, Beijing Municipality, 100000, China

  • Beijing Friendship Hospital

    Beijing, Beijing Municipality, 100050, China

  • Beijing LuHe Hospital

    Beijing, Beijing Municipality, 101199, China

  • Beijing Tong Ren Hospital

    Beijing, Beijing Municipality, 100730, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102218, China

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, China

  • Fuwai Hospital Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100037, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100032, China

Conditions

The condition(s) this trial relates to.

acute coronary syndrome Angina, Stable coronary artery disorder intermediate coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.