Can a single shot stop clots? a new drug puts the idea to the test

NCT ID NCT03384966

Completed Disease control Sponsor: Viatris Innovation GmbH Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial investigates whether a single injection of selatogrel can quickly prevent platelets from clumping together in people with stable coronary artery disease. Researchers are also checking how fast the drug works, how long it lasts, and whether injecting it in the thigh or belly makes a difference. The study involves about 346 adults with stable coronary artery disease and compares selatogrel to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: an injectable drug called selatogrel that prevents platelets from clumping together
What this could lead to: If it works, selatogrel could offer a fast-acting, easy-to-use option for preventing heart attacks in people with stable coronary artery disease.
What could go wrong: This is a Phase 2 trial, so the drug is still being tested for safety and effectiveness. It may not work as hoped or could cause side effects like bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STABLE CORONARY ARTERY DISEASE

Contacts and locations

Locations

Aarhus University Hospital

Aarhus, 8200, Denmark
East & North Hertfordshire NHS Trust - Lister Hospital

Stevenage, SG14AB, United Kingdom
Florida Hospital Tampa - Pepin Heart Institute

Tampa, Florida, 33613, United States
Freeman Hospital - Cardiothoracic Department

Newcastle upon Tyne, NE7 7DN, United Kingdom
Indiana University School of Medicine - Krannert Institute of Cardiology

Indianapolis, Indiana, 46202, United States
Inova Cardiology

Lutherville, Maryland, 21093, United States
Inova Center for Thrombosis Research and Translational Medicine

Falls Church, Virginia, 22042, United States
Institut de Cardiologie de Montréal

Montreal, Quebec, H1T 1C8, Canada
Maastricht UMC

Maastricht, 6229 HX, Netherlands
Mount Sinai Hospital (New York)

New York, New York, 10029, United States
National Heart Centre Singapore

Singapore, 169609, Singapore
NorthShore University

Chicago, Illinois, 73104, United States
Rigshospitalet

Copenhagen, 2100, Denmark
Sahlgrenska University Hospital

Gothenburg, 40530, Sweden
Sheffield Teaching Hospitals

Sheffield, S5 7AU, United Kingdom
St. Antonius Ziekenhuis

Nieuwegein, 3435 CM, Netherlands
Universitats-Herzzentrum

Bad Krozingen, 79189, Germany
University Medical Center Groningen

Groningen, 9713 GZ, Netherlands
University of Florida (UF) Jacksonville

Jacksonville, Florida, 32209, United States
Uppsala University Hospital

Uppsala, 18288, Sweden

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