Can obese people tolerate glucagon? small study aims to find out
NCT ID NCT02817659
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study tests how well 20 healthy obese adults tolerate increasing doses of glucagon, a hormone that raises blood sugar. Researchers measure nausea levels to find the highest dose people can handle before feeling sick. The goal is simply to understand tolerability, not to treat obesity directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Glucagon
What this could lead to
If successful, this could help design future treatments that use glucagon for weight management.
What could go wrong
This is a very small, early-phase study focused only on tolerability, not on weight loss or any disease outcome. Results may not lead to a practical treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Translational Research Institute for Metabolism and Diabetes
Orlando, Florida, 32804, United States