Brain cancer trial tests G-CSF to shield thinking skills

NCT ID NCT06649851

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 13 times

Summary

This study tests whether a drug called G-CSF (filgrastim) can help preserve brain structure and thinking abilities in people with a specific type of glioblastoma (MGMT-methylated) who are receiving standard chemotherapy and radiation. About 60 participants will be randomly assigned to receive G-CSF or not, and researchers will measure brain volume changes and cognitive function over a year. The goal is to reduce brain damage from cancer treatment, not to cure the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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