MGMT-METHYLATED GLIOBLASTOMA
Clinical trials for MGMT-METHYLATED GLIOBLASTOMA explained in plain language.
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Promising new combo may extend life in aggressive brain cancer
Disease control Recruiting nowThis study tests whether adding another chemotherapy drug (lomustine) to the standard treatment can help people with a specific type of glioblastoma, a fast-growing brain cancer, live longer. About 200 adults aged 18-70 with newly diagnosed, MGMT-methylated glioblastoma will be r…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE3 • Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New hope for brain cancer: experimental virus therapy targets aggressive gliomas
Disease control Recruiting nowThis study tests whether adding two experimental drugs, DB107-RRV and DB107-FC, to standard treatment (radiation and chemotherapy) can help people with newly diagnosed high grade glioma, a fast-growing brain cancer. About 70 adults aged 18-75 will receive the drugs during and aft…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Could a common drug shield the brain from chemo-radiation damage in glioblastoma?
Disease control Recruiting nowThis study tests whether giving G-CSF (a drug that boosts white blood cells) alongside standard chemoradiation can help preserve brain structure and thinking abilities in people with a specific type of glioblastoma (MGMT-methylated). About 60 newly diagnosed patients will be rand…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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Could a new drug combo extend life in aggressive brain cancer?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC