Sound waves could tame Parkinson's tremors and twitches

NCT ID NCT03319485

Ongoing Disease control Sponsor: InSightec Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a non-invasive treatment using focused ultrasound to target a small area in the brain that controls movement. It is for people with advanced Parkinson's disease whose medication no longer controls their involuntary movements or motor fluctuations. The goal is to see if this one-time procedure can safely reduce these symptoms and improve daily function.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

Azienda Ospedaliera Universitaria di Verona, Univerista di Verona

Verona, 37134, Italy
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
CINAC-Hospital HM Puerta del Sur

Móstoles, Madrid, 28938, Spain
Chang Bing Show Chwan Memorial Hospital

Changhua, Taiwan
Clinica Universidad De Navarra

Pamplona, Navarre, 31008, Spain
Fondazione IRCCS Neurological Institute Carlo Besta

Milan, 20133, Italy
Mayo Clinic

Rochester, Minnesota, 55905, United States
New York University Health Langone

New York, New York, 10016, United States
Palm Beach Neuroscience Institute/Sperling Medical Group

Boynton Beach, Florida, 33472, United States
Pennsylvania Hospital Department of Neurosurgery

Philadelphia, Pennsylvania, 19106, United States
Rambam Health Care

Haifa, 3109601, Israel
Severance Hospital, Yonsei University Health System

Seoul, South Korea
St. Mary's Hospital

London, United Kingdom
Stanford University Medical Center

Stanford, California, 94305, United States
Swedish Medical Center

Seattle, Washington, 98122, United States
The Ohio State Wexner Medical Center

Columbus, Ohio, 43210, United States
Toronto Western Hospital

Toronto, Ontario, M5T 2S8, Canada
University of Maryland Medical System

Baltimore, Maryland, 21201, United States
University of Virginia Health System

Charlottesville, Virginia, 22908, United States
Weill Cornell Medicine

New York, New York, 10065, United States

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