Precision radiation may tame prostate cancer with fewer side effects
NCT ID NCT05616650
First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 6 times
Summary
This phase II trial is testing a focused, high-dose radiation therapy (SBRT) given in just two sessions for men with early-stage prostate cancer that hasn't spread. The goal is to see if this approach can destroy the tumor while avoiding the side effects of treating the whole prostate. Participants will receive a special imaging tracer to help target the radiation precisely, and will be followed for two years with scans and a final biopsy to check if the cancer is gone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stereotactic body radiation therapy (SBRT) and a single dose of 18F-DCFPyL (a radioactive tracer for imaging)
- What this could lead to
- If successful, this could offer a less invasive treatment option for early-stage prostate cancer with fewer side effects than whole-gland surgery or radiation.
- What could go wrong
- This is a small, early-phase trial with only 42 participants, so results may not apply to all patients. The treatment may not fully eliminate the cancer, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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