New scan could predict hormone therapy success in breast cancer
NCT ID NCT02409316
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a special PET/CT scan using a radioactive tracer called FES to see estrogen receptor activity in women with advanced, hormone-resistant breast cancer. The goal was to see if the scan could predict how well a new hormone therapy would work. Only 6 people were enrolled before the study was stopped early, so the findings are very limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [18F]Fluoroestradiol (FES) - a radioactive tracer used in PET/CT scans
- What this could lead to
- If successful, this imaging method could help doctors predict how well hormone therapy will work in metastatic breast cancer, guiding more personalized treatment.
- What could go wrong
- This was a very small, early-phase study that was terminated early, so results are limited. The scan is not yet proven to improve outcomes and may not be widely available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pennsylvania Hospital
Philadelphia, Pennsylvania, 19104, United States
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