Egg-Freezing showdown: tamoxifen vs letrozole for breast cancer patients
NCT ID NCT03011684
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether tamoxifen or letrozole works better for preserving fertility in women with estrogen-sensitive breast cancer before starting chemotherapy. About 309 participants will take one of the two drugs during ovarian stimulation to freeze their eggs. The main goal is to see which drug leads to more mature eggs retrieved.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tamoxifen and letrozole (oral drugs)
What this could lead to
If it works, this could help doctors choose the best drug to maximize egg yield for fertility preservation in breast cancer patients.
What could go wrong
This trial is still recruiting and results are not yet available. The drugs may not differ significantly in egg yield, and individual responses vary.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California at San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••