Poop pills could soothe troubled tummies

NCT ID NCT05740319

Recruiting now Symptom relief Sponsor: Shanghai Zhongshan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether transplanting gut bacteria from healthy donors can relieve symptoms of irritable bowel syndrome (IBS). 102 adults who haven't responded to at least three standard treatments will receive donor bacteria either in capsules or through a tube into the nose and gut once a month for three months. Researchers will track symptom changes, quality of life, and side effects for six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fecal microbiota transplantation (FMT)
What this could lead to: If it works, this could offer a new way to ease IBS symptoms for people who haven't gotten relief from standard treatments.
What could go wrong: This is an early-stage trial with no placebo group, so results may be due to chance. FMT can cause mild side effects like bloating or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

Zhongshan Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200032, China

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