Could a poop pill lift depression and soothe IBS?

NCT ID NCT05174273

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether taking fecal microbiota transplantation (FMT) pills can improve symptoms of major depressive disorder (MDD) and irritable bowel syndrome (IBS). About 133 adults with MDD, with or without IBS, will either receive FMT or continue their usual treatment. Researchers will measure changes in depression and IBS severity over time.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Calgary, TRW building

    Calgary, Alberta, T2N 4Z6, Canada