Stool test could shorten h. pylori treatment to just 7 days

NCT ID NCT07405697

Not yet recruiting Disease control Sponsor: Shanghai Zhongshan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 7-day course of antibiotics chosen by a stool test works as well as a 14-day course for people with stubborn H. pylori infections. About 290 adults who have failed previous treatment will get a stool test to find which drugs their infection resists, then be randomly assigned to 7 or 14 days of tailored therapy. The goal is to see if the shorter treatment is just as effective, safer, and cheaper.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A combination of antibiotics and acid-reducing drugs chosen based on a stool test
What this could lead to: If successful, this could make H. pylori rescue treatment shorter, cheaper, and more effective by using a simple stool test to guide drug choice.
What could go wrong: This is a Phase 4 trial, but it's not yet recruiting. The shorter 7-day course might not work as well as 14 days, and the stool test may not be widely available.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HELICOBACTER PYLORI INFECTION

Contacts and locations

Locations

Renji Hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, Shanghai Municipality, 200000, China
Shanghai Jiangong Hospitail.

Shanghai, Shanghai Municipality, China
Shanghai Tenth People Hospital

Shanghai, Shanghai Municipality, China
Zhongshan Hospital, Fudan University

Shanghai, China

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