Blood RNA may reveal hidden liver cancers

NCT ID NCT02908048

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether tiny bits of RNA in the blood can serve as markers for liver disease and liver cancer. Researchers collected blood samples from nearly 1,900 people with liver cancer, cirrhosis, or chronic liver disease. The goal was to see if these RNA markers could help diagnose cancer and predict how well a patient responds to treatment or if cancer returns after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to detect liver cancer earlier and monitor for recurrence after treatment.

What could go wrong

The study was terminated early, so results may be incomplete. It is an observational study, not a treatment trial, so no direct benefit to participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CIRRHOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bile duct neoplasm biliary tract cancer Biliary Tract Neoplasms cholangiocarcinoma cirrhosis of liver Fibrosis hepatitis hepatocellular carcinoma liver disorder Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • McGuire VA Medical Center

    Richmond, Virginia, 23249, United States

  • The University of Chicago Medical Center

    Chicago, Illinois, 60637, United States