Can PRP shots boost exercise benefits for creaky knees?
NCT ID NCT04697667
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether adding platelet-rich plasma (PRP) injections to a supervised exercise program helps people with knee osteoarthritis more than exercise alone. 84 adults aged 40-70 with moderate knee arthritis took part. Researchers measured pain, function, and movement to see which approach worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Platelet-rich plasma (PRP) injection
What this could lead to
If it works, this could offer a better way to manage knee osteoarthritis pain and function without surgery.
What could go wrong
This is a small, completed trial (84 people) comparing combinations of exercise and PRP. Results may not apply to everyone, and PRP is not a cure—effects may be temporary.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Istanbul University-Cerrahpasa
Istanbul, Turkey (Türkiye)