Weight-Loss drug users: will exercise save your muscle?

NCT ID NCT06645470

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at what happens to your body when you take anti-obesity medications like semaglutide or tirzepatide, and whether adding aerobic or resistance exercise helps preserve muscle and bone while losing fat. About 40 adults will be assigned to either standard care (medication only) or supervised exercise sessions three times a week for six months. Researchers will measure changes in body composition, fitness, strength, and quality of life to find the best approach for healthy weight loss.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••